Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.77 |
| ▸ | EGFR | P00533 | 1/20 | 0.77 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.77 |
| ▸ | CDK4 | P11802 | 1/20 | 0.77 |
| ▸ | CCND1 | P24385 | 1/20 | 0.77 |
| ▸ | FLT3 | P36888 | 1/20 | 0.77 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.77 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.77 |
| ▸ | RYR1 | P21817 | 10/20 | 0.73 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bastadin 20 SCHEMBL6796056 | 1.00 | AURKA (0.77) | AURKAEGFRERBB2CDK4CCND1 | |
| Bastadin 7 SCHEMBL4338482 | 0.89 | RYR1 (0.92) | AURKAEGFRERBB2CDK4CCND1 | |
| SCHEMBL20365680 | 0.53 | RYR1 (0.55) | RYR1FKBP1A | |
| SCHEMBL31443844 | 0.51 | PARP10 (0.56) | — | |
| SCHEMBL7977984 | 0.49 | TUBB4A (0.60) | AURKACDK4CCND1FLT3AURKB | |
| SCHEMBL11180783 | 0.48 | MEN1 (0.39) | RYR1FKBP1A | |
| SCHEMBL7262152 | 0.48 | CRBN (0.46) | — | |
| SCHEMBL3727752 | 0.47 | PARP10 (0.42) | — | |
| SCHEMBL17018289 | 0.47 | MAPT (0.43) | — | |
| SCHEMBL2983127 | 0.47 | FABP6 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6734211-B1 | FOR STIMULATING NERVE CELL GROWTH IN A SUBJECT COMPRISING ADMINISTERING TO THE SUBJECT A BASTADIN COMPOUND OR ITS ANALOGS | OREGON HEALTH & SCIENCES UNIVERSITY | 2004-05-11 | — | — | US | disclosed |