Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803006 | 1.00 | GRIN1 (0.50) | GRIN1GRIN2AGRIN2BHSD11B1GRM4 | |
| SCHEMBL15998490 | 0.95 | GRIN1 (0.44) | GRIN1GRIN2AGRIN2BHSD11B1GRM4 | |
| SCHEMBL9965971 | 0.91 | GRM4 (0.44) | GRIN1GRIN2AGRIN2BGRM4MAPK1 | |
| SCHEMBL8627193 | 0.81 | GRIN1 (0.46) | GRIN1GRIN2AGRIN2BHSD11B1GRM4 | |
| SCHEMBL27796313 | 0.81 | GRIN1 (0.43) | GRIN1GRIN2AGRIN2BHSD11B1GRM4 | |
| SCHEMBL12259535 | 0.77 | GRIN1 (0.41) | GRIN1GRIN2AGRIN2BHSD11B1GRM4 | |
| Hydrochloric Acid SCHEMBL5874306 | 0.77 | ALDH1A1 (0.38) | GRIN1GRIN2AGRIN2BGRM4MAPK1 | |
| Hydrochloric Acid SCHEMBL5874153 | 0.77 | ALDH1A1 (0.38) | GRIN1GRIN2AGRIN2BGRM4MAPK1 | |
| SCHEMBL9963369 | 0.75 | GRIN1 (0.42) | GRIN1GRIN2AGRIN2BHSD11B1GRM4 | |
| SCHEMBL30825709 | 0.75 | GRIN1 (0.58) | GRIN1GRIN2AGRIN2BHSD11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | GRIN1 780/4885GRIN2A 1010/4885GRIN2B 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.