Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 7/20 | 0.41 |
| ▸ | RXRB | P28702 | 7/20 | 0.41 |
| ▸ | RXRG | P48443 | 7/20 | 0.41 |
| ▸ | SLC26A3 | P40879 | 5/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615 | 0.92 | FFAR1 (0.50) | ANO1FFAR4FFAR1PPARGPPARD | |
| SCHEMBL6660 | 0.91 | SYK (0.41) | ANO1 | |
| SCHEMBL7483 | 0.86 | ANO1 (0.37) | SLC26A3ANO1FFAR4FFAR1 | |
| SCHEMBL6869 | 0.86 | SYK (0.41) | ANO1FFAR4FFAR1 | |
| SCHEMBL2012 | 0.86 | LPAR1 (0.43) | LPAR1ANO1LPAR3NR1H4 | |
| SCHEMBL6585 | 0.84 | EPHX1 (0.42) | LPAR1RXRARXRBRXRGLPAR2 | |
| SCHEMBL2232 | 0.82 | LMNA (0.39) | LPAR1ANO1LPAR3 | |
| SCHEMBL6424 | 0.81 | MEN1 (0.37) | ANO1 | |
| SCHEMBL6805 | 0.81 | LPAR1 (0.42) | LPAR1RXRARXRBRXRGSLC26A3 | |
| SCHEMBL17265471 | 0.78 | LPAR1 (0.41) | LPAR1RXRARXRBRXRGSLC26A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483252-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-08-08 | — | — | EP | claimed |
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | claimed |
| EP-2483252-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |