Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806409 | 0.97 | TUBB1 (0.48) | TUBB1PPARGPPARA | |
| SCHEMBL6803968 | 0.92 | TUBB1 (0.60) | TUBB1PPARGPPARA | |
| SCHEMBL6804778 | 0.92 | TUBB1 (0.52) | TUBB1 | |
| SCHEMBL6803333 | 0.91 | TUBB1 (0.59) | TUBB1 | |
| SCHEMBL6810275 | 0.89 | TUBB1 (0.56) | TUBB1PPARGPPARA | |
| SCHEMBL6807317 | 0.88 | TUBB1 (0.56) | TUBB1 | |
| SCHEMBL6673511 | 0.87 | TUBB1 (0.44) | TUBB1PPARGPPARA | |
| SCHEMBL6673533 | 0.85 | TUBB1 (0.62) | TUBB1 | |
| SCHEMBL29511164 | 0.84 | TUBB1 (0.49) | TUBB1 | |
| SCHEMBL22069860 | 0.82 | TUBB1 (0.49) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040121965-A1 | Method of treating resistant tumors | WYETH HOLDINGS CORPORATION (US) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121965-A1 | Method of treating resistant tumors | SLC11A2, VHL, REN | TUBB1 199/4885PPARG 2118/4885PPARA 1366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.