Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 19/20 | 0.57 |
| ▸ | STS | P08842 | 6/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801380 | 0.88 | CYP19A1 (0.62) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6801011 | 0.88 | CYP19A1 (0.61) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6797851 | 0.88 | CYP19A1 (0.67) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6806213 | 0.84 | CYP19A1 (0.61) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6801901 | 0.84 | CYP19A1 (0.56) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6800102 | 0.82 | CYP19A1 (0.60) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL27545671 | 0.82 | CYP11B2 (0.42) | CYP19A1 | |
| SCHEMBL6801145 | 0.81 | GAA (0.54) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6799481 | 0.81 | MAOB (0.56) | CYP19A1 | |
| SCHEMBL9226442 | 0.79 | CYP11B2 (0.42) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |