Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.62 |
| ▸ | BCHE | P06276 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503765 | 0.83 | HTR2A (0.59) | HTR2ABCHEKMT2AMEN1ATM | |
| SCHEMBL11883481 | 0.82 | GAA (0.58) | HTR2ABCHEKMT2AMEN1ATM | |
| SCHEMBL11880287 | 0.81 | GAA (0.60) | HTR2ABCHEKMT2AMEN1 | |
| SCHEMBL29194688 | 0.79 | BCHE (0.80) | HTR2ABCHEKMT2AMEN1ATM | |
| SCHEMBL23023138 | 0.79 | HTR2A (0.86) | HTR2AHTR2CMTNR1AMTNR1B | |
| SCHEMBL31332137 | 0.79 | HTR2A (0.86) | HTR2AHTR2CMTNR1AMTNR1B | |
| SCHEMBL10032816 | 0.79 | MEN1 (0.85) | BCHEKMT2AMEN1ATM | |
| SCHEMBL12131075 | 0.79 | MEN1 (0.85) | BCHEKMT2AMEN1ATM | |
| SCHEMBL17754723 | 0.78 | APLNR (0.58) | HTR2AKMT2AMEN1HTR2C | |
| SCHEMBL11092418 | 0.77 | BCHE (0.64) | HTR2ABCHEKMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385494-A2 | AEROSOL COMPOSITIONS CONTAINING FORMOTEROL AND A STEROID SUCH AS E.G. BUDESONIDE OR FLUTICASONE FOR DELIVERY INTO THE LUNGS | Dey L.P. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083113-A2 | AEROSOL COMPOSITIONS CONTAINING FORMOTEROL AND A STEROID SUCH AS E.G. BUDESONIDE OR FLUTICASONE FOR DELIVERY INTO THE LUNGS VIA NEBULIZATION | DEY, L.P. (US) | 2002-10-24 | — | — | WO | disclosed |