Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 11/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809647 | 0.92 | ESR1 (0.36) | ESR1KCNH2ACACBCYP1A2CYP2D6 | |
| SCHEMBL6801169 | 0.90 | AGBL2 (0.39) | ESR1KCNH2ACACBCYP1A2NPC1 | |
| SCHEMBL6806643 | 0.86 | ACACB (0.41) | ACACBRAB9A | |
| SCHEMBL6804725 | 0.79 | ESR1 (0.43) | ESR1KCNH2ACACBCYP1A2CYP2D6 | |
| SCHEMBL6805279 | 0.79 | CNR1 (0.42) | ESR1KCNH2ACACBCYP1A2CYP2D6 | |
| SCHEMBL6540778 | 0.78 | CYP1A2 (0.51) | ESR1KCNH2ACACBCYP1A2CYP2D6 | |
| SCHEMBL4474242 | 0.78 | CYP1A2 (0.51) | ESR1KCNH2ACACBCYP1A2CYP2D6 | |
| SCHEMBL6677150 | 0.78 | CYP1A2 (0.51) | ESR1KCNH2ACACBCYP1A2CYP2D6 | |
| SCHEMBL6805002 | 0.77 | CNR1 (0.40) | ESR1KCNH2ACACBCYP1A2CYP2D6 | |
| SCHEMBL6917853 | 0.76 | ESR1 (0.41) | ESR1KCNH2ACACBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | ESR1 3850/4885KCNH2 184/4885ACACB 1800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.