Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172285 | 0.89 | TSHR (0.59) | TSHRCYP1A2CYP2C19CYP2D6CYP2C9 | |
| Dinitrophenylene SCHEMBL27675225 | 0.89 | CYP1A2 (0.59) | TSHRCYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL9175089 | 0.88 | TSHR (0.57) | TSHRCYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL24767335 | 0.86 | TSHR (0.56) | TSHRCYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL8733292 | 0.86 | TSHR (0.56) | TSHRCYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL10650120 | 0.85 | TSHR (0.54) | TSHRCYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL29385659 | 0.85 | TSHR (0.67) | TSHRCYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL132216 | 0.85 | TSHR (0.67) | TSHRCYP1A2CYP2C19CYP2D6CYP2C9 | |
| Nitrogen SCHEMBL9102089 | 0.84 | TSHR (0.53) | TSHRCYP1A2CYP2C19CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL6961845 | 0.84 | TSHR (0.53) | TSHRCYP1A2CYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103313964-A | Intermediate compounds and methods for preparing fingolimod | MAPI PHARMA LTD | 2013-09-18 | — | — | CN | claimed |
| EP-1015402-B1 | Method for producing compounds containing fluorine, in particular fluorobenzaldehydes and fluorobenzonitriles | CLARIANT GMBH (DE) | 2002-12-04 | — | — | EP | claimed |
| US-6166242-A | Method for producing compounds containing fluorine, in particular fluorobenzaldhydes and fluorobenzonitriles | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 2000-12-26 | — | — | US | claimed |
| CN-1268936-A | Method for producing compound contg. fluorine, in particular fluorobenzaldhydes and fluorobnzonitriles | AVENTIS RES & TECHNOLOGY GMBH (DE) | 2000-10-04 | — | — | CN | claimed |
| EP-1015402-A1 | METHOD FOR PRODUCING COMPOUNDS CONTAINING FLUORINE, IN PARTICULAR FLUOROBENZALDHYDES AND FLUOROBENZONITRILES | Aventis Research & Technologies GmbH & Co. KG (DE) | 2000-07-05 | — | — | EP | claimed |
| WO-1999011588-A1 | METHOD FOR PRODUCING COMPOUNDS CONTAINING FLUORINE, IN PARTICULAR FLUOROBENZALDHYDES AND FLUOROBENZONITRILES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-03-11 | — | — | WO | claimed |
| US-20240231230-A1 | COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM | NISSAN CHEMICAL CORPORATION (JP) | 2024-07-11 | — | — | US | disclosed |
| US-20210186970-A1 | SELECTIVE CALCIUM CHANNEL ANTAGONISTS | NORTHWESTERN UNIVERSITY | 2021-06-24 | — | — | US | disclosed |
| WO-2021113686-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |
| US-20200377446-A1 | METHOD FOR MANUFACTURING AROMATIC AZO COMPOUND | FUJIFILM CORPORATION (JP) | 2020-12-03 | — | — | US | disclosed |
| US-10639310-B2 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE CORPORATION (US) | 2020-05-05 | — | — | US | disclosed |
| US-20190167685-A1 | SELECTIVE CALCIUM CHANNEL ANTAGONISTS | NORTHWESTERN UNIVERSITY | 2019-06-06 | — | — | US | disclosed |
| US-20190125750-A1 | HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AND PYRROLO[2,3-b]PYRIMIDINES AS JANUS KINASE INHIBITORS | INCYTE CORPORATION | 2019-05-02 | — | — | US | disclosed |
| EP-1189929-A2 | FACTOR VIIA INHIBITORS | Aventis Pharma Deutschland GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-6166242-A | Method for producing compounds containing fluorine, in particular fluorobenzaldhydes and fluorobenzonitriles | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 2000-12-26 | — | — | US | disclosed |
| WO-2000075172-A2 | FACTOR VIIa INHIBITORS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-12-14 | — | — | WO | disclosed |
| EP-1059302-A1 | Factor VIIa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2000-12-13 | — | — | EP | disclosed |
| CN-1268936-A | Method for producing compound contg. fluorine, in particular fluorobenzaldhydes and fluorobnzonitriles | AVENTIS RES & TECHNOLOGY GMBH (DE) | 2000-10-04 | — | — | CN | disclosed |
| EP-1015402-A1 | METHOD FOR PRODUCING COMPOUNDS CONTAINING FLUORINE, IN PARTICULAR FLUOROBENZALDHYDES AND FLUOROBENZONITRILES | Aventis Research & Technologies GmbH & Co. KG (DE) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999011588-A1 | METHOD FOR PRODUCING COMPOUNDS CONTAINING FLUORINE, IN PARTICULAR FLUOROBENZALDHYDES AND FLUOROBENZONITRILES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10639310-B2 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | JAK3, JAK1, JAK2 | TSHR 3192/4885CYP1A2 1683/4885CYP2C19 1587/4885 |
| US-20190167685-A1 | SELECTIVE CALCIUM CHANNEL ANTAGONISTS | CACNA1C, CACNA1B, CACNA1G | TSHR 4014/4885CYP1A2 4681/4885CYP2C19 4851/4885 |
| US-20200377446-A1 | METHOD FOR MANUFACTURING AROMATIC AZO COMPOUND | CYP4X1, ALDOA, PAH | TSHR 4517/4885CYP1A2 15/4885CYP2C19 62/4885 |
| US-20190125750-A1 | HETEROARYL SUBSTITUTED PYRROLO[2,3-b]PYRIDINES AND PYRROLO[2,3-b]PYRIMIDINES AS JANUS KINASE INHIBITORS | JAK3, JAK1, JAK2 | TSHR 3192/4885CYP1A2 1683/4885CYP2C19 1587/4885 |
| US-20210186970-A1 | SELECTIVE CALCIUM CHANNEL ANTAGONISTS | CACNA1C, CACNA1B, CACNA1G | TSHR 4014/4885CYP1A2 4681/4885CYP2C19 4851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.