Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680864 | 1.00 | ADRB3 (0.45) | ADRB3LPAR1LPAR5ADRB1BACE1 | |
| SCHEMBL6682203 | 0.95 | ADRB3 (0.44) | ADRB3LPAR1LPAR5ADRB1BACE1 | |
| SCHEMBL6682206 | 0.95 | ADRB3 (0.44) | ADRB3LPAR1LPAR5ADRB1BACE1 | |
| SCHEMBL6805016 | 0.93 | ADRB3 (0.47) | ADRB3LPAR1LPAR5ADRB1SLC2A1 | |
| SCHEMBL6682294 | 0.93 | ADRB3 (0.47) | ADRB3LPAR1LPAR5ADRB1SLC2A1 | |
| SCHEMBL6540663 | 0.92 | CYP4F2 (0.36) | ADRB3BACE1 | |
| SCHEMBL6540667 | 0.92 | CYP4F2 (0.36) | ADRB3BACE1 | |
| SCHEMBL6677324 | 0.91 | ADRB3 (0.55) | ADRB3LPAR1LPAR5ADRB1 | |
| SCHEMBL6541363 | 0.91 | TP53 (0.40) | ADRB3ADRB1BACE1 | |
| SCHEMBL6541360 | 0.91 | TP53 (0.40) | ADRB3ADRB1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | ADRB3 150/4885LPAR1 1110/4885LPAR5 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.