Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 17/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805016 | 0.93 | ADRB3 (0.47) | ADRB3LPAR1LPAR5ADRB1 | |
| SCHEMBL6682294 | 0.93 | ADRB3 (0.47) | ADRB3LPAR1LPAR5ADRB1 | |
| SCHEMBL6540282 | 0.91 | ADRB3 (0.42) | ADRB3ADRB1 | |
| SCHEMBL6540274 | 0.91 | ADRB3 (0.42) | ADRB3ADRB1 | |
| SCHEMBL6806565 | 0.91 | ADRB3 (0.45) | ADRB3LPAR1LPAR5ADRB1 | |
| SCHEMBL6680864 | 0.91 | ADRB3 (0.45) | ADRB3LPAR1LPAR5ADRB1 | |
| SCHEMBL6541170 | 0.91 | ADRB3 (0.46) | ADRB3LPAR1LPAR5ADRB1 | |
| SCHEMBL6541176 | 0.91 | ADRB3 (0.46) | ADRB3LPAR1LPAR5ADRB1 | |
| SCHEMBL6804154 | 0.89 | ADRB3 (0.52) | ADRB3ADRB1 | |
| SCHEMBL6677354 | 0.88 | ADRB3 (0.50) | ADRB3LPAR1LPAR5ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |