Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806656 | 0.95 | CARM1 (0.42) | MCHR1DRD2HTR1AHTR2ASLC6A4 | |
| SCHEMBL6807423 | 0.88 | PIM1 (0.45) | DRD2PARP1PRKD3PIM1SRC | |
| SCHEMBL6806588 | 0.88 | AURKB (0.55) | PARP1PARP2PRKD3PIM1SRC | |
| SCHEMBL6811032 | 0.88 | PIM1 (0.45) | DRD2PARP1PRKD3PIM1SRC | |
| SCHEMBL6805548 | 0.88 | PIM1 (0.45) | DRD2PARP1PRKD3PIM1SRC | |
| SCHEMBL6810078 | 0.87 | DRD2 (0.45) | DRD2PARP1PRKD3PIM1SRC | |
| SCHEMBL6805777 | 0.87 | PRKD3 (0.53) | DRD2PRKD3PIM1SRCFLT4 | |
| SCHEMBL6803660 | 0.87 | PIM1 (0.46) | DRD2PRKD3PIM1SRCFLT4 | |
| SCHEMBL6806647 | 0.83 | PIM1 (0.55) | PARP1PARP2PRKD3PIM1SRC | |
| SCHEMBL6805715 | 0.83 | PIM1 (0.51) | PARP1PRKD3PIM1SRCFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |