Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14198170 | 0.85 | NPFFR1 (0.40) | ALDH1A1PTGS1PTGS2TP53TDP1 | |
| SCHEMBL1984944 | 0.84 | ALDH1A1 (0.39) | ALDH1A1PTGS1PTGS2TP53TDP1 | |
| SCHEMBL9996969 | 0.80 | NPFFR2 (0.53) | ALDH1A1NPFFR1NPFFR2HDAC8 | |
| Ethane SCHEMBL2153516 | 0.78 | ALDH1A1 (0.55) | ALDH1A1PTGS1PTGS2TDP1NPFFR1 | |
| SCHEMBL11661768 | 0.78 | ALDH1A1 (0.40) | ALDH1A1PTGS1PTGS2TP53TDP1 | |
| SCHEMBL10896146 | 0.78 | TP53 (0.42) | ALDH1A1PTGS1PTGS2TP53TDP1 | |
| SCHEMBL666188 | 0.76 | ALDH1A1 (0.55) | ALDH1A1PTGS1PTGS2TP53TDP1 | |
| SCHEMBL10866846 | 0.76 | ALDH1A1 (0.39) | ALDH1A1PTGS1PTGS2TP53TDP1 | |
| SCHEMBL25665110 | 0.76 | PTGS1 (0.43) | ALDH1A1PTGS1PTGS2TP53TDP1 | |
| SCHEMBL14761235 | 0.76 | ALDH1A1 (0.34) | ALDH1A1PTGS1PTGS2TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6734269-B1 | Method for controlled free radical polymerization or copolymerization of ethylene under high pressure in the presence of an initiator-controller | ATOFINA (FR) | 2004-05-11 | — | — | US | disclosed |
| US-4178327-A | FIREPROOFING | THE DOW CHEMICAL COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4054733-A | MOLDING MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1977-10-18 | — | — | US | disclosed |