SCHEMBL6807345

SCHEMBL6807345

CCC(C)(CC)C(=O)NCCCCCCNC(=O)C(C)(CC)CC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.53
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.48
ALDH1A1 P00352 1/20 0.48
POLB P06746 1/20 0.48
KDM4E B2RXH2 1/20 0.46
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46
CASP2 P42575 1/20 0.42
CA12 O43570 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16318168 0.94 EPHX1 (0.48) EPHX1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL6812216 0.92 EPHX1 (0.47) EPHX1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL13165954 0.87 EPHX1 (0.43) EPHX1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL10018015 0.85 PAOX (0.44) EPHX1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL4546721 0.82 EPHX1 (0.53) EPHX1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL14134865 0.82 EPHX1 (0.53) EPHX1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL27784617 0.82 EPHX1 (0.54) EPHX1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL21126141 0.81 KDM4E (0.52) EPHX1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL20243892 0.80 KDM4E (0.44) EPHX1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL38652872 0.79 EPHX1 (0.61) EPHX1MEN1KMT2ACASP2ZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230384671-A1 LAMINATE OF NEGATIVE TONE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING NEGATIVE TONE LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2023-11-30 US disclosed
US-11543750-B2 Lithographic printing plate precursor and method for producing lithographic printing plate FUJIFILM CORPORATION (JP) 2023-01-03 US disclosed
US-20210181631-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PREPARING PLANOGRAPHIC PRINTING PLATE, PLANOGRAPHIC PRINTING METHOD, AND CURABLE COMPOSITION FUJIFILM CORPORATION (JP) 2021-06-17 US disclosed
US-10668764-B2 Lithographic printing plate precursor, manufacturing method therefor, plate manufacturing method for lithographic printing plate, and printing method FUJIFILM CORPORATION (JP) 2020-06-02 US disclosed
US-20200166846-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2020-05-28 US disclosed
US-20200117086-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2020-04-16 US disclosed
US-20070231740-A1 A planographic printing plate precursor comprising: an aluminum support; and a photosensitive layer including a polymerization initiator, a polymerizable compound and a binder polymer; an oxygen barrier layer; and a protective layer including a filler; capable of image formation FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed