Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807345 | 0.85 | EPHX1 (0.53) | EPHX1POLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8986779 | 0.84 | PAOX (0.44) | PAOXEPHX1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL10024184 | 0.82 | PAOX (0.34) | PAOXEPHX1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9355619 | 0.81 | POLB (0.50) | PAOXEPHX1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL16318168 | 0.80 | EPHX1 (0.48) | EPHX1POLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16189982 | 0.80 | GNAI3 (0.63) | GNAI3GNAO1GNAI1DPP7RRM1 | |
| SCHEMBL9499965 | 0.79 | PAOX (0.47) | PAOXEPHX1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL14077026 | 0.79 | EPHX1 (0.35) | PAOXEPHX1ALDH1A1GNAI3GNAO1 | |
| SCHEMBL6812216 | 0.78 | EPHX1 (0.47) | EPHX1POLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16256508 | 0.78 | PAOX (0.52) | PAOXEPHX1POLBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107264-A1 | NUCLEIC ACID DELIVERY COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120107264-A1 | NUCLEIC ACID DELIVERY COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-05-03 | — | — | US | disclosed |
| US-7459151-B2 | Phosphate-binding polymers for oral administration | GENZYME CORPORATION (US) | 2008-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107264-A1 | NUCLEIC ACID DELIVERY COMPOUNDS | HNRNPH3, NSUN2, SNRPA | PAOX 3982/4885EPHX1 4691/4885POLB 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.