Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL8343260 | 0.90 | ALDH1A1 (0.45) | ALDH1A1ATMKMT2AGAAMEN1 | |
| SCHEMBL6807407 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ALOX5LMNAKMT2AGAA | |
| SCHEMBL2680565 | 0.80 | ERCC5 (0.52) | ALDH1A1ALOX5ATMPTPN1KMT2A | |
| SCHEMBL501135 | 0.79 | — | — | |
| SCHEMBL3084306 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL9402312 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ALOX5ATMKMT2AMEN1 | |
| SCHEMBL11677596 | 0.78 | — | — | |
| Methane SCHEMBL11616604 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ALOX5ATMKMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL28112564 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ALOX5ATMKMT2AMEN1 | |
| SCHEMBL10484371 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ALOX5ATMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828427-B1 | Oligomeric aminodiol-containing compounds, libraries thereof, and process of preparing the same | ISIS PHARMACEUTICALS, INC. | 2004-12-07 | — | — | US | disclosed |
| US-6750344-B1 | MONOCYCLIC AMINE SCAFFOLD BEARING AT LEAST TWO SITES OF DIVERSITY, CYCLIZED TO FORM BICYCLIC AMINE SCAFFOLDS; 7-AMINO-PYRROLO(1,2-A)PYRAZIN-4-ONE COMPOUNDS | ISIS PHARMACEUTICALS, INC. | 2004-06-15 | — | — | US | disclosed |
| EP-1204671-B1 | FLUOROGENIC COMPOUNDS AND USES THEREFOR | 3M INNOVATIVE PROPERTIES CO (US) | 2003-12-03 | — | — | EP | disclosed |
| US-6566508-B2 | Compound for use in the accurate detection of food parasites | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-20 | — | — | US | disclosed |
| US-20020147317-A1 | Fluorogenic compounds and uses therefor | 3M INNOVATIVE PROPETIES COMPANY | 2002-10-10 | — | — | US | disclosed |
| EP-1204671-A1 | FLUOROGENIC COMPOUNDS AND USES THEREFOR | 3M Innovative Properties Company (US) | 2002-05-15 | — | — | EP | disclosed |
| US-6372895-B1 | USEFUL IN ASSAYING FOR BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES COMPANY | 2002-04-16 | — | — | US | disclosed |
| US-6316626-B1 | Amine compounds and combinatorial libraries comprising same | ISIS PHARMACEUTICALS, INC. | 2001-11-13 | — | — | US | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| WO-2001010881-A1 | FLUOROGENIC COMPOUNDS AND USES THEREFOR | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-02-15 | — | — | WO | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147317-A1 | Fluorogenic compounds and uses therefor | NOTUM, WEE1, CPSF7 | ALDH1A1 762/4885ALOX5 2031/4885ATM 4608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.