Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
| ▸ | MC1R | Q01726 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807840 | 1.00 | PNMT (0.48) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL9188893 | 0.89 | PNMT (0.49) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL4970480 | 0.89 | PNMT (0.49) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL3484494 | 0.89 | PNMT (0.49) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL4131017 | 0.86 | PNMT (0.44) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL8008416 | 0.86 | PNMT (0.44) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL8190225 | 0.85 | PNMT (0.50) | PNMTHTR7HTR2BNPC1RAB9A | |
| Bromide SCHEMBL15671137 | 0.85 | PNMT (0.54) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL6807838 | 0.85 | PNMT (0.47) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL6810950 | 0.84 | PNMT (0.49) | PNMTHTR7HTR2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134778-B | Charge inversion type polymer micelle, drug-loaded micelle and preparation method thereof | 西南民族大学 | 2021-03-09 | — | — | CN | disclosed |
| US-20040204348-A1 | Cyclic peptide ligands that target urokinase plasminogen activator receptor | THE ANGSTROM PHARMACEUTICALS, INC. | 2004-10-14 | — | — | US | disclosed |
| EP-0804456-A4 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS INC (US) | 1999-05-19 | — | — | EP | disclosed |
| EP-0804456-A1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS, INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996011205-A9 | PEPTIDE NUCLEIC ACID CONJUGATES | — | 1996-05-30 | — | — | WO | disclosed |
| WO-1996011205-A1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS, INC. (US) | 1996-04-18 | — | — | WO | disclosed |
| EP-0538399-A4 | — | — | 1994-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204348-A1 | Cyclic peptide ligands that target urokinase plasminogen activator receptor | PLAUR, PLAU, PLG | PNMT 4622/4885HTR7 2978/4885HTR2B 2618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.