SCHEMBL6808396

SCHEMBL6808396

O=C(CCc1cc(/N=N/c2ccccc2C(=O)O)ccc1O)ON1C(=O)CCC1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.49
KMT2A Q03164 7/20 0.49
MAPT P10636 5/20 0.49
NPSR1 Q6W5P4 3/20 0.49
GAA P10253 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
IDE P14735 1/20 0.44
MYC P01106 1/20 0.38
TDP1 Q9NUW8 4/20 0.38
THRB P10828 2/20 0.38
PSMD14 O00487 1/20 0.38
HSP90AA1 P07900 1/20 0.38
MMP2 P08253 1/20 0.38
MAPK1 P28482 1/20 0.38
PDE4A P27815 1/20 0.37
BLVRB P30043 1/20 0.37
KDR P35968 1/20 0.37
HTT P42858 1/20 0.37
PSMB8 P28062 1/20 0.35
PSMB5 P28074 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6808391 1.00 MEN1 (0.49) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL5409457 0.88 GAA (0.43) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL5409463 0.88 GAA (0.43) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL5415637 0.84 MEN1 (0.43) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL7129515 0.84 MEN1 (0.43) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL6812010 0.82 MEN1 (0.60) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL6812006 0.82 MEN1 (0.60) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL14503974 0.79 MEN1 (0.42) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL6808385 0.77 MEN1 (0.52) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL5409453 0.76 MEN1 (0.44) MEN1KMT2AMAPTNPSR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6602987-B1 4'-hydroxyazobenzene-2-carboxylic acid (HABA) compounds; useful as reagents for labeling, isolation and detection of biological molecules YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2003-08-05 US claimed
US-20040067229-A1 Azobenzene derivatives as labeling agents and intermediates thereof YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2004-04-08 US disclosed
US-6602987-B1 4'-hydroxyazobenzene-2-carboxylic acid (HABA) compounds; useful as reagents for labeling, isolation and detection of biological molecules YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2003-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040067229-A1 Azobenzene derivatives as labeling agents and intermediates thereof CBR1, CBR3, HBB MEN1 2043/4885KMT2A 1572/4885MAPT 2644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.