Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 3/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | MTTP | P55157 | 8/20 | 0.46 |
| ▸ | APOB | P04114 | 6/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6806268 | 0.91 | SMO (0.56) | SMOMTTPAPOBTRPV1 | |
| SCHEMBL6805320 | 0.90 | SMO (0.55) | SMOMTTPAPOBTRPV1 | |
| SCHEMBL6809534 | 0.83 | SMO (0.48) | SMONR3C1MTTPAPOB | |
| Hydrochloric Acid SCHEMBL6668967 | 0.82 | HDAC1 (0.46) | SMO | |
| SCHEMBL6667324 | 0.81 | SMO (0.45) | SMO | |
| SCHEMBL6804665 | 0.81 | SMO (0.56) | SMONR3C1MTTPAPOBTRPV1 | |
| SCHEMBL6802666 | 0.80 | SMO (0.57) | SMOMTTPAPOBTRPV1 | |
| SCHEMBL6919444 | 0.79 | SMO (0.54) | SMOMTTPAPOBTRPV1 | |
| SCHEMBL6804857 | 0.79 | SMO (0.64) | SMONR3C1MTTPAPOB | |
| SCHEMBL6788033 | 0.78 | SMO (0.67) | SMONR3C1MTTPAPOBTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | SMO 4390/4885NR3C1 224/4885MTTP 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.