Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | HTR1D | P28221 | 8/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR1B | P28222 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812077 | 0.84 | HTR1D (0.43) | HTR1DDRD2HTR2AHTR1AHTR1B | |
| SCHEMBL5097946 | 0.84 | HTR1D (0.43) | HTR1DDRD2HTR2AHTR1AHTR1B | |
| SCHEMBL5093705 | 0.82 | HTR1D (0.52) | HTR1DDRD2HTR2AHTR1AHTR1B | |
| SCHEMBL6811129 | 0.82 | HTR1D (0.52) | HTR1DDRD2HTR2AHTR1AHTR1B | |
| SCHEMBL6811827 | 0.80 | HTR1D (0.42) | HTR1DDRD2HTR2AHTR1AHTR1B | |
| SCHEMBL6808310 | 0.76 | ESR1 (0.36) | HTR1DDRD2HTR2AHTR1AHTR1B | |
| SCHEMBL5093583 | 0.76 | THRB (0.36) | HTR1DDRD2HTR2AHTR1AHTR1B | |
| SCHEMBL6812492 | 0.75 | HTR1D (0.39) | HTR1DDRD2HTR2AHTR1AHTR1B | |
| SCHEMBL6812483 | 0.75 | HTR1D (0.39) | HTR1DDRD2HTR2AHTR1AHTR1B | |
| SCHEMBL5092141 | 0.74 | HTR1D (0.34) | HTR1DDRD2HTR2AHTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | CYP2D6, LPXN, CYP1B1 | ROCK2 2286/4885HTR1D 124/4885DRD2 1606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.