Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19130275 | 1.00 | NPSR1 (0.55) | NPSR1MAPTALDH1A1HTTHDAC3 | |
| SCHEMBL4008749 | 0.81 | NPSR1 (0.59) | NPSR1MAPTALDH1A1HTTHSD17B10 | |
| SCHEMBL27602261 | 0.80 | NPSR1 (0.58) | NPSR1MAPTALDH1A1HTTHSD17B10 | |
| SCHEMBL22090177 | 0.79 | NPSR1 (0.60) | NPSR1MAPTALDH1A1HTTHSD17B10 | |
| SCHEMBL5417523 | 0.79 | NPSR1 (0.49) | NPSR1MAPTALDH1A1HSD17B10TDP1 | |
| SCHEMBL7512186 | 0.78 | NPSR1 (0.46) | NPSR1MAPTALDH1A1HTTHSD17B10 | |
| SCHEMBL3270454 | 0.78 | MAPT (0.50) | NPSR1MAPTALDH1A1HTTNPC1 | |
| SCHEMBL3270451 | 0.78 | MAPT (0.50) | NPSR1MAPTALDH1A1HTTNPC1 | |
| SCHEMBL22204543 | 0.77 | NPSR1 (0.51) | NPSR1MAPTALDH1A1HTTHSD17B10 | |
| SCHEMBL6810221 | 0.77 | CES1 (0.51) | ALDH1A1HTTHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014161-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2004-01-22 | — | — | US | disclosed |