Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810221 | 1.00 | CES1 (0.51) | CES1CES2CYP19A1ALDH1A1LMNA | |
| SCHEMBL7912766 | 0.95 | TDP1 (0.52) | CES1CES2ALDH1A1LMNAPOLB | |
| SCHEMBL4800395 | 0.87 | CYP19A1 (0.49) | CES1CES2CYP19A1ALDH1A1LMNA | |
| SCHEMBL9778344 | 0.84 | POLB (0.58) | CES1CES2CYP19A1ALDH1A1LMNA | |
| SCHEMBL7110437 | 0.82 | ALDH1A1 (0.58) | CES1CES2CYP19A1ALDH1A1LMNA | |
| SCHEMBL8961556 | 0.82 | ALDH1A1 (0.58) | CES1CES2CYP19A1ALDH1A1LMNA | |
| SCHEMBL13176247 | 0.82 | ALDH1A1 (0.58) | CES1CES2CYP19A1ALDH1A1LMNA | |
| SCHEMBL27479898 | 0.82 | ALDH1A1 (0.50) | CES1CES2CYP19A1ALDH1A1LMNA | |
| SCHEMBL27963785 | 0.81 | PTPRC (0.59) | CES1CES2ALDH1A1LMNAPOLB | |
| SCHEMBL73063 | 0.81 | HDAC3 (0.61) | CES1ALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014161-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2004-01-22 | — | — | US | disclosed |
| US-20020177180-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2002-11-28 | — | — | US | disclosed |
| EP-1090139-A1 | PH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | Thermogen, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067420-A1 | pH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | THERMOGEN, INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| US-5026897-A | Chemically mask cholinesterase enzymes; antispasmotic agents | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1991-06-25 | — | — | US | disclosed |
| US-4973734-A | ANTIDIOTE FOR ORGANOPPHOSPHATE POISONING | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1990-11-27 | — | — | US | disclosed |