Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.70 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.66 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.58 |
| ▸ | ABL1 | P00519 | 7/20 | 0.43 |
| ▸ | RET | P07949 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681919 | 0.90 | PIK3CD (0.69) | PIK3CDPIK3CGPIK3C2BABL1RET | |
| SCHEMBL685439 | 0.85 | PIK3CG (0.71) | PIK3CDPIK3CGPIK3C2BABL1PIK3CA | |
| SCHEMBL682358 | 0.84 | PIK3CG (0.67) | PIK3CDPIK3CGPIK3C2BABL1RET | |
| SCHEMBL681998 | 0.83 | PIK3CG (0.70) | PIK3CDPIK3CGPIK3C2BABL1PIK3CA | |
| SCHEMBL681700 | 0.83 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3C2BPIK3CAPIK3CB | |
| SCHEMBL682314 | 0.79 | PIK3CG (1.00) | PIK3CDPIK3CGPIK3C2BABL1PIK3CA | |
| SCHEMBL682384 | 0.78 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3C2BABL1RET | |
| SCHEMBL681988 | 0.78 | PIK3CG (0.82) | PIK3CDPIK3CGPIK3C2BABL1PIK3CA | |
| SCHEMBL680957 | 0.76 | PIK3CD (0.88) | PIK3CDPIK3CGPIK3C2BPIK3CAPIK3CB | |
| SCHEMBL680950 | 0.76 | PIK3CG (0.60) | PIK3CDPIK3CGPIK3C2BABL1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790228-B2 | Heterocyclic kinase inhibitors | INTELLIKINE LLC (US) | 2017-10-17 | — | — | US | disclosed |
| US-9790228-B2 | Heterocyclic kinase inhibitors | INTELLIKINE LLC (US) | 2017-10-17 | — | — | US | disclosed |
| EP-2346508-B1 | HETEROCYCLIC KINASE INHIBITORS | INTELLIKINE LLC (US) | 2016-08-24 | — | — | EP | disclosed |
| US-20160168157-A1 | HETEROCYCLIC KINASE INHIBITORS | INTELLIKINE LLC | 2016-06-16 | — | — | US | disclosed |
| US-20160168157-A1 | HETEROCYCLIC KINASE INHIBITORS | INTELLIKINE LLC | 2016-06-16 | — | — | US | disclosed |
| US-9296742-B2 | Heterocyclic kinase inhibitors | INTELLIKINE LLC (US) | 2016-03-29 | — | — | US | disclosed |
| US-9296742-B2 | Heterocyclic kinase inhibitors | INTELLIKINE LLC (US) | 2016-03-29 | — | — | US | disclosed |
| US-20140206685-A1 | HETEROCYCLIC KINASE INHIBITORS | INTELLIKINE LLC (US) | 2014-07-24 | — | — | US | disclosed |
| US-20140206685-A1 | HETEROCYCLIC KINASE INHIBITORS | INTELLIKINE LLC (US) | 2014-07-24 | — | — | US | disclosed |
| US-20110281866-A1 | HETEROCYCLIC KINASE INHIBITORS | INTELLIKINE, INC. (US) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168157-A1 | HETEROCYCLIC KINASE INHIBITORS | MAP3K13, MAP3K3, CDK3 | PIK3CD 147/4885PIK3CG 191/4885PIK3C2B 132/4885 |
| US-20140206685-A1 | HETEROCYCLIC KINASE INHIBITORS | MAP3K13, MAP3K3, CDK3 | PIK3CD 147/4885PIK3CG 191/4885PIK3C2B 132/4885 |
| US-20110281866-A1 | HETEROCYCLIC KINASE INHIBITORS | MAP3K13, MAP3K3, CDK3 | PIK3CD 147/4885PIK3CG 191/4885PIK3C2B 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.