Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.56 |
| ▸ | PIK3C2B | O00750 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.41 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681991 | 0.88 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3C2BCYP1A2MAPT | |
| SCHEMBL681922 | 0.81 | PIK3CG (0.61) | PIK3CGPIK3CDPIK3C2BCYP1A2CYP2C19 | |
| SCHEMBL681998 | 0.81 | PIK3CG (0.70) | PIK3CGPIK3CDPIK3C2BSRCABL1 | |
| SCHEMBL685439 | 0.79 | PIK3CG (0.71) | PIK3CGPIK3CDPIK3C2BSRCABL1 | |
| SCHEMBL682009 | 0.79 | PIK3CD (0.85) | PIK3CGPIK3CDPIK3C2B | |
| SCHEMBL680945 | 0.76 | PIK3CD (0.70) | PIK3CGPIK3CDPIK3C2BSRCABL1 | |
| SCHEMBL682314 | 0.75 | PIK3CG (1.00) | PIK3CGPIK3CDPIK3C2BSRCABL1 | |
| SCHEMBL681988 | 0.73 | PIK3CG (0.82) | PIK3CGPIK3CDPIK3C2BSRCABL1 | |
| SCHEMBL681731 | 0.72 | PIK3CD (1.00) | PIK3CGPIK3CDPIK3C2BPIK3CAPIK3CB | |
| SCHEMBL15892694 | 0.71 | PIK3CD (0.86) | PIK3CGPIK3CDPIK3C2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110281866-A1 | HETEROCYCLIC KINASE INHIBITORS | INTELLIKINE, INC. (US) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110281866-A1 | HETEROCYCLIC KINASE INHIBITORS | MAP3K13, MAP3K3, CDK3 | PIK3CG 191/4885PIK3CD 147/4885PIK3C2B 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.