Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.66 |
| ▸ | MC3R | P41968 | 6/20 | 0.48 |
| ▸ | MC5R | P33032 | 4/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | MC1R | Q01726 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809668 | 1.00 | MC4R (0.66) | MC4RMC3RMC5RAKT1MC1R | |
| SCHEMBL6252826 | 0.79 | MC4R (0.47) | MC4R | |
| SCHEMBL4515320 | 0.79 | MC4R (0.63) | MC4RAKT1 | |
| SCHEMBL6809963 | 0.78 | MC4R (0.42) | MC4RMC3R | |
| SCHEMBL4679456 | 0.73 | MC4R (0.59) | MC4RAKT1 | |
| SCHEMBL4678279 | 0.73 | MC4R (0.54) | MC4RAKT1 | |
| SCHEMBL6809537 | 0.71 | MC4R (0.53) | MC4RAKT1 | |
| SCHEMBL14355904 | 0.71 | AKT1 (0.60) | MC4RAKT1 | |
| SCHEMBL5337821 | 0.70 | MC4R (0.64) | MC4RAKT1 | |
| SCHEMBL4682255 | 0.70 | AKT1 (0.62) | MC4RAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053933-A1 | Ligands of melanocortin receptors and compositions and methods related thereto | NEUROCRINE BIOSCIENCES, INC. | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053933-A1 | Ligands of melanocortin receptors and compositions and methods related thereto | MC3R, MC1R, MC5R | MC4R 4/4885MC3R 1/4885MC5R 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.