Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.51 |
| ▸ | AKT1 | P31749 | 6/20 | 0.49 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | AKT1S1 | Q96B36 | 1/20 | 0.45 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515320 | 0.85 | MC4R (0.63) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL4679456 | 0.79 | MC4R (0.59) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL6809533 | 0.79 | MC4R (0.39) | MC4RDPP7 | |
| SCHEMBL4678279 | 0.78 | MC4R (0.54) | MC4RAKT1AKT2AKT1S1AKT3 | |
| Hydrochloric Acid SCHEMBL4516761 | 0.73 | AKT1 (0.58) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL5337821 | 0.73 | MC4R (0.64) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL4682255 | 0.72 | AKT1 (0.62) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL6157624 | 0.72 | MC4R (0.59) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL5483959 | 0.72 | MC4R (0.63) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL6809670 | 0.71 | MC4R (0.66) | MC4RAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053933-A1 | Ligands of melanocortin receptors and compositions and methods related thereto | NEUROCRINE BIOSCIENCES, INC. | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053933-A1 | Ligands of melanocortin receptors and compositions and methods related thereto | MC3R, MC1R, MC5R | MC4R 4/4885DPP7 2162/4885AKT1 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.