Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.62 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 5/20 | 0.31 |
| ▸ | MMP3 | P08254 | 4/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804948 | 0.92 | TUBB1 (0.63) | TUBB1MMP2MMP3MMP1HDAC1 | |
| SCHEMBL6675810 | 0.90 | TUBB1 (0.61) | TUBB1MMP2MMP3MMP1MMP8 | |
| SCHEMBL6675817 | 0.90 | TUBB1 (0.61) | TUBB1MMP2MMP3MMP1MMP8 | |
| SCHEMBL6810366 | 0.90 | TUBB1 (0.65) | TUBB1MMP2MMP3MMP13 | |
| Hydrochloric Acid SCHEMBL6670866 | 0.90 | TUBB1 (0.60) | TUBB1MMP2MMP3MMP1MMP8 | |
| Hydrochloric Acid SCHEMBL6670873 | 0.90 | TUBB1 (0.60) | TUBB1MMP2MMP3MMP1MMP8 | |
| SCHEMBL6804951 | 0.89 | TUBB1 (0.64) | TUBB1MMP1 | |
| SCHEMBL6670636 | 0.88 | TUBB1 (0.63) | TUBB1MMP2MMP3MMP1MMP8 | |
| SCHEMBL6670644 | 0.88 | TUBB1 (0.63) | TUBB1MMP2MMP3MMP1MMP8 | |
| Trifluoroacetic Acid SCHEMBL6806174 | 0.88 | TUBB1 (0.58) | TUBB1MMP2MMP3MMP1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040121965-A1 | Method of treating resistant tumors | WYETH HOLDINGS CORPORATION (US) | 2004-06-24 | — | — | US | claimed |
| US-20040121965-A1 | Method of treating resistant tumors | WYETH HOLDINGS CORPORATION (US) | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121965-A1 | Method of treating resistant tumors | SLC11A2, VHL, REN | TUBB1 199/4885ADAMTS4 493/4885ADAMTS5 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.