Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778648 | 0.86 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL8251411 | 0.86 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL2778650 | 0.86 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL2779598 | 0.86 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL4620535 | 0.86 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL23911772 | 0.86 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL4619744 | 0.86 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL8249516 | 0.86 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL10041961 | 0.85 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 | |
| SCHEMBL10075505 | 0.85 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216033-C | Process for the cis-selective catalytic hydrogenation of cyclohexylidene amines | CIBA SC HOLDING AG (CH) | 2005-08-24 | — | — | CN | disclosed |
| EP-1064250-B1 | PROCESS FOR THE CIS-SELECTIVE CATALYTIC HYDROGENATION OF CYCLOHEXYLIDENAMINES | CIBA SC HOLDING AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| US-6232501-B1 | HYDROGENATING CYCLOHEXYLIDENAMINE IN PRESENCE OF COPPER CONTAINING CATALYST, OR REACTING KETONE WITH COMPOUND INTRODUCING ALKYLAMINE GROUP, HYDROGENATING IMINE OR NITRONE FORMED IN PRESENCE OF SAID CATALYST TO PRODUCE CYCLOHEXYLAMINE | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-05-15 | — | — | US | disclosed |
| EP-1064250-A1 | PROCESS FOR THE CIS-SELECTIVE CATALYTIC HYDROGENATION OF CYCLOHEXYLIDENAMINES | Ciba SC Holding AG (CH) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999047486-A1 | PROCESS FOR THE CIS-SELECTIVE CATALYTIC HYDROGENATION OF CYCLOHEXYLIDENAMINES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-09-23 | — | — | WO | disclosed |