Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | PLD2 | O14939 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5896977 | 0.99 | ITGB3 (0.44) | ITGB3ITGA2BKDM4EALOX15DRD2 | |
| SCHEMBL5677479 | 0.95 | ITGB3 (0.46) | ITGB3ITGA2BKDM4EDRD2DRD3 | |
| SCHEMBL5896871 | 0.94 | ITGB3 (0.46) | ITGB3ITGA2BKDM4EDRD2DRD3 | |
| SCHEMBL5896860 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BKDM4EALOX15DRD2 | |
| SCHEMBL5896620 | 0.81 | KDM4E (0.50) | ITGB3ITGA2BKDM4EALOX15PLD2 | |
| SCHEMBL5677017 | 0.81 | ITGB3 (0.49) | ITGB3ITGA2BKDM4EALDH1A1MAPT | |
| SCHEMBL5677289 | 0.81 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EPLD2PLD1 | |
| SCHEMBL5889476 | 0.81 | KDM4E (0.61) | ITGB3ITGA2BKDM4EALOX15DRD2 | |
| SCHEMBL5896655 | 0.80 | KDM4E (0.51) | ITGB3ITGA2BKDM4EPLD2PLD1 | |
| Hydrochloric Acid SCHEMBL6809892 | 0.80 | HDAC2 (0.44) | ITGB3ITGA2BKDM4EPLD2PLD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | ZC3HAV1, TYR, ZC3HAV1L | ITGB3 4436/4885ITGA2B 4759/4885KDM4E 986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.