Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805111 | 0.90 | ACACB (0.48) | ACACBCA2SYKNPSR1ESR1 | |
| SCHEMBL6540336 | 0.88 | ACACB (0.52) | ACACBLMNACA2NPSR1ESR1 | |
| SCHEMBL6541476 | 0.83 | ACACB (0.40) | ACACBBDKRB1CA2ESR1KCNH2 | |
| SCHEMBL6804168 | 0.83 | ACACB (0.47) | ACACBLMNACA2NPSR1ESR1 | |
| SCHEMBL6805221 | 0.82 | ACACB (0.48) | ACACBLMNACA2NPSR1ESR1 | |
| SCHEMBL6541158 | 0.82 | KMT2A (0.45) | ACACBCA2ESR1KCNH2 | |
| SCHEMBL6540340 | 0.82 | KMT2A (0.45) | ACACBCA2ESR1KCNH2 | |
| SCHEMBL6676950 | 0.82 | ACACB (0.43) | ACACBLMNA | |
| SCHEMBL6541568 | 0.79 | CA2 (0.45) | LMNABCL2L1MCL1CA2 | |
| SCHEMBL6682412 | 0.78 | ACACB (0.41) | ACACBBDKRB1LMNAESR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | ACACB 1800/4885BDKRB1 665/4885LMNA 3890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.