Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071127 | 0.94 | TDP1 (0.56) | KDM4ECYP1A2LMNACCR1CCR5 | |
| SCHEMBL30374920 | 0.94 | TDP1 (0.56) | KDM4ECYP1A2LMNACCR1CCR5 | |
| SCHEMBL29742341 | 0.92 | TDP1 (0.54) | KDM4ECYP1A2LMNACCR1CCR5 | |
| SCHEMBL9039356 | 0.92 | TDP1 (0.54) | KDM4ECYP1A2LMNACCR1CCR5 | |
| SCHEMBL29742339 | 0.92 | TDP1 (0.54) | KDM4ECYP1A2LMNACCR1CCR5 | |
| SCHEMBL245713 | 0.92 | TDP1 (0.54) | KDM4ECYP1A2LMNACCR1CCR5 | |
| SCHEMBL8902116 | 0.85 | KDM4E (0.56) | KDM4ECYP1A2LMNACCR1CCR5 | |
| SCHEMBL17721314 | 0.78 | KDM4E (0.43) | KDM4ECYP1A2LMNACCR1CCR5 | |
| SCHEMBL10382864 | 0.74 | PPARA (0.39) | CYP1A2TDP1GRM5F2RL1 | |
| SCHEMBL2174836 | 0.73 | KDM4E (0.46) | KDM4ECYP1A2LMNACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731207-A2 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | Merck Sharp & Dohme LLC (US) | 2026-04-29 | — | — | EP | disclosed |
| WO-2025006293-A2 | INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS | MERCK SHARP & DOHME LLC (US) | 2025-01-02 | — | — | WO | disclosed |
| US-6733905-B2 | SUCH AS BIS(1-(2-PYRIDYL)CYCLOPENTENE-N,C2)(ACETYLACETNONATO) IRIDIDIUM(III); ELECTROLUMINESCENCE/PHOSPHORESCENCE; EFFICIENCY; LOW EXCITATION STATE | CANON KABUSHIKI KAISHA (JP) | 2004-05-11 | — | — | US | disclosed |
| US-20020094453-A1 | Metal coordination compound, luminescence device and display apparatus | CANON KABUSHIKI KAISHA (JP) | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094453-A1 | Metal coordination compound, luminescence device and display apparatus | ICOSLG, CCRL2, ZC3HAV1L | KDM4E 3942/4885CYP1A2 2361/4885LMNA 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.