SCHEMBL6810850

SCHEMBL6810850

Nc1ccc(NC(=O)c2ccccc2O)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.74
MEN1 O00255 5/20 0.73
KMT2A Q03164 5/20 0.73
TP53 P04637 4/20 0.73
HTT P42858 4/20 0.73
KDM4E B2RXH2 3/20 0.73
HSD17B10 Q99714 2/20 0.73
HPGD P15428 1/20 0.73
NPC1 O15118 4/20 0.70
RAB9A P51151 3/20 0.70
POLB P06746 2/20 0.70
SMN1; SMN2 Q16637 2/20 0.70
NFKB1 P19838 1/20 0.70
NFKB2 Q00653 1/20 0.70
RELA Q04206 1/20 0.70
PLAU P00749 2/20 0.67
F2 P00734 1/20 0.67
F10 P00742 1/20 0.67
PLG P00747 1/20 0.67
PLAT P00750 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18327174 0.91 LMNA (0.89) LMNAMEN1KMT2ATP53HTT
SCHEMBL8402954 0.89 KMT2A (0.64) LMNAMEN1KMT2ATP53HTT
Osalmid SCHEMBL29928981 0.85 LMNA (1.00) LMNAMEN1KMT2ATP53HTT
Osalmid SCHEMBL220088 0.85 LMNA (1.00) LMNAMEN1KMT2ATP53HTT
Salicylanilide SCHEMBL152221 0.85 MEN1 (1.00) LMNAMEN1KMT2ATP53HTT
Salicylanilide SCHEMBL28262329 0.85 MEN1 (1.00) LMNAMEN1KMT2ATP53HTT
Salicylanilide SCHEMBL20165864 0.85 MEN1 (1.00) LMNAMEN1KMT2ATP53HTT
Salicylanilide SCHEMBL14051034 0.85 MEN1 (1.00) LMNAMEN1KMT2ATP53HTT
SCHEMBL9322019 0.85 LMNA (0.54) LMNAMEN1KMT2ATP53HTT
Osalmid SCHEMBL28180566 0.84 LMNA (0.90) LMNAMEN1KMT2ATP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108864618-B High-antibacterial wear-resistant PVC resin material and preparation method thereof 界首市汇锦塑胶有限公司 2020-07-03 CN claimed
CN-109134927-B Antibacterial plasticizing auxiliary agent for PVC and preparation method thereof 扬州天喜塑胶有限公司 2020-06-12 CN claimed
CN-109134927-A A kind of PVC antibacterial plasticizing adjuvant and preparation method thereof 李丹丹 2019-01-04 CN claimed
CN-108864618-A A kind of high antibacterial wear-resisting PVC resin material and preparation method thereof 李丹丹 2018-11-23 CN claimed
CN-109305925-B Multifunctional bio-based phenol amine antioxidant, and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-03-08 CN disclosed
CN-108864618-B High-antibacterial wear-resistant PVC resin material and preparation method thereof 界首市汇锦塑胶有限公司 2020-07-03 CN disclosed
CN-109134927-B Antibacterial plasticizing auxiliary agent for PVC and preparation method thereof 扬州天喜塑胶有限公司 2020-06-12 CN disclosed
CN-109134927-B Antibacterial plasticizing auxiliary agent for PVC and preparation method thereof 扬州天喜塑胶有限公司 2020-06-12 CN disclosed
CN-109134927-A A kind of PVC antibacterial plasticizing adjuvant and preparation method thereof 李丹丹 2019-01-04 CN disclosed
CN-108864618-A A kind of high antibacterial wear-resisting PVC resin material and preparation method thereof 李丹丹 2018-11-23 CN disclosed
CN-1165531-C Alpha-methylbenzyl-containing thiourea inhibitors of herpes viruses containing phenylenediamine groups 2004-09-08 CN disclosed
EP-1137632-B1 THIOUREA INHIBITORS OF HERPES VIRUSES WYETH CORP (US) 2004-07-28 EP disclosed
WO-2000034268-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034261-A2 HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034269-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034238-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034260-A2 ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034258-A2 HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034237-A2 ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
EP-0409070-A2 Mesogenic cyanite functional maleimides and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP disclosed