Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873143 | 0.86 | FTO (0.50) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL9016356 | 0.84 | FTO (0.48) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL29472215 | 0.83 | FTO (0.55) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL16544 | 0.83 | FTO (0.55) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL5664537 | 0.82 | FTO (0.51) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL10486825 | 0.82 | FTO (0.54) | FTOMAPTHPGDMEN1HTT | |
| Hydrochloric Acid SCHEMBL5440613 | 0.82 | FTO (0.54) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL9013831 | 0.82 | FTO (0.54) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL7970051 | 0.82 | HPGD (0.52) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL8515794 | 0.81 | FTO (0.50) | FTOMAPTHPGDMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040204348-A1 | Cyclic peptide ligands that target urokinase plasminogen activator receptor | THE ANGSTROM PHARMACEUTICALS, INC. | 2004-10-14 | — | — | US | disclosed |
| EP-1144604-A1 | CYCLIC PEPTIDE LIGANDS THAT TARGET UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR, THEIR PHARMACEUTICAL COMPOSITIONS AND USE | Angstrom Pharmaceuticals, inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| US-6277818-B1 | ANTITUMOR AGENT, ANTICANCER AGENTS | ANGSTROM PHARMACEUTICALS, INC. | 2001-08-21 | — | — | US | disclosed |
| WO-2000026353-A1 | CYCLIC PEPTIDE LIGANDS THAT TARGET UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR, THEIR PHARMACEUTICAL COMPOSITIONS AND USE | ANGSTROM PHARMACEUTICALS, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204348-A1 | Cyclic peptide ligands that target urokinase plasminogen activator receptor | PLAUR, PLAU, PLG | FTO 3910/4885MAPT 3989/4885HPGD 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.