Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186007 | 0.95 | HTR2A (0.73) | HTR2ADRD2 | |
| SCHEMBL6185890 | 0.84 | HTR2A (0.66) | HTR2ADRD2 | |
| SCHEMBL6219456 | 0.82 | HTR1A (0.53) | HTR2ADRD2 | |
| SCHEMBL6187384 | 0.80 | HTR2A (0.90) | HTR2ADRD2 | |
| SCHEMBL6811168 | 0.79 | HTR2A (1.00) | HTR2ADRD2 | |
| SCHEMBL6747915 | 0.79 | HTR1A (0.60) | HTR2ADRD2 | |
| SCHEMBL6188307 | 0.79 | HTR2A (0.73) | HTR2ADRD2 | |
| SCHEMBL6205666 | 0.78 | HTR2A (0.90) | HTR2ADRD2 | |
| Hydrochloric Acid SCHEMBL6185203 | 0.78 | HTR2A (0.98) | HTR2ADRD2 | |
| Hydrochloric Acid SCHEMBL6187796 | 0.78 | HTR2A (0.72) | HTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067960-A1 | Heterocyclic substituted piperazines for the treatment of schizophrenia | DAVIS JAMIE MARIE (US) | 2004-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067960-A1 | Heterocyclic substituted piperazines for the treatment of schizophrenia | HTR2C, CNR1, HTR2A | HTR2A 3/4885DRD2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.