Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | LDHB | P07195 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815676 | 0.83 | ALDH1A1 (0.52) | CA1CA2TDP1KMT2AMEN1 | |
| SCHEMBL3532005 | 0.81 | TDP1 (0.62) | TDP1KMT2AALDH1A1POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4672680 | 0.80 | TDP1 (0.60) | TDP1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL16296096 | 0.79 | CA1 (0.64) | CA1CA2LDHALDHBTDP1 | |
| SCHEMBL18263633 | 0.77 | SMN1; SMN2 (0.68) | CA1CA2HDAC6ALDH1A1POLB | |
| Diphenylmethane SCHEMBL11159603 | 0.75 | MEN1 (0.67) | CA1CA2TDP1HDAC8HDAC6 | |
| SCHEMBL28807804 | 0.75 | CA1 (0.59) | CA1CA2LDHALDHBTDP1 | |
| SCHEMBL13614230 | 0.74 | TDP1 (0.53) | TDP1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL6815374 | 0.74 | POLB (0.73) | TDP1KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL3562210 | 0.74 | TDP1 (0.67) | TDP1KMT2AALDH1A1POLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004012656-A2 | THIOPHENE AND FURAN DERIVATIVES AS PROSTAGLANDIN AGONISTS AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-02-12 | — | — | WO | claimed |
| WO-2004012656-A2 | THIOPHENE AND FURAN DERIVATIVES AS PROSTAGLANDIN AGONISTS AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-02-12 | — | — | WO | disclosed |