Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA7 | P43166 | 9/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 9/20 | 0.48 |
| ▸ | CA1 | P00915 | 9/20 | 0.48 |
| ▸ | CA2 | P00918 | 9/20 | 0.48 |
| ▸ | CA12 | O43570 | 8/20 | 0.48 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 4/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811274 | 0.84 | PNMT (0.40) | CA7CA14CA1CA2CA12 | |
| SCHEMBL6811267 | 0.84 | HTR2C (0.42) | CA7CA14CA1CA2CA12 | |
| SCHEMBL6812143 | 0.79 | CA14 (0.42) | CA7CA14CA1CA2CA12 | |
| SCHEMBL6812048 | 0.78 | HTR1D (0.56) | DRD2DRD4HTR1DHTR1BHTR1A | |
| SCHEMBL5093578 | 0.78 | HTR1D (0.56) | DRD2DRD4HTR1DHTR1BHTR1A | |
| SCHEMBL5090707 | 0.76 | PNMT (0.41) | DRD2DRD4PNMTHTR1DHTR1B | |
| SCHEMBL5088620 | 0.76 | PNMT (0.41) | DRD2DRD4PNMTHTR1DHTR1B | |
| SCHEMBL7408325 | 0.76 | XBP1 (0.40) | DRD2DRD4HTR1DHTR1BHTR1A | |
| SCHEMBL7401152 | 0.76 | HTR1D (0.46) | DRD2DRD4HTR1DHTR1BHTR1A | |
| SCHEMBL8550172 | 0.76 | HTR1D (0.46) | DRD2DRD4HTR1DHTR1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | CYP2D6, LPXN, CYP1B1 | CA7 1618/4885CA14 1543/4885CA1 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.