SCHEMBL681132

SCHEMBL681132

C=CCOC(=O)C1=C(CC2CO2)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 2/20 0.35
TSHR P16473 1/20 0.35
MAPT P10636 3/20 0.33
RHOA P61586 1/20 0.33
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
KDM4E B2RXH2 3/20 0.32
HPGD P15428 2/20 0.32
TP53 P04637 1/20 0.32
SNCA P37840 1/20 0.32
LMNA P02545 2/20 0.30
GAA P10253 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20183947 0.78 CYP3A4 (0.53) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL724602 0.73 TP53 (0.30) TP53SMN1; SMN2
SCHEMBL436695 0.72 CYP3A4 (0.47) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL7174680 0.71 CYP3A4 (0.50) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL20695812 0.71 CYP3A4 (0.50) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL18317991 0.70 SNCA (0.50) CYP3A4ALDH1A1HSD17B10TSHRMEN1
SCHEMBL19628364 0.70 ALDH1A1 (0.46) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL20183970 0.70 CYP3A4 (0.48) CYP3A4ALDH1A1HSD17B10TSHRMAPT
Vinyl Chloride SCHEMBL9716793 0.69 CYP3A4 (0.44) CYP3A4ALDH1A1HSD17B10TSHRMAPT
SCHEMBL3257967 0.68 ALDH1A1 (0.47) CYP3A4ALDH1A1HSD17B10TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7025696-B2 Golf ball containing graphite nanosheets in a polymeric network ACUSHNET COMPANY (US) 2006-04-11 US claimed
US-6802784-B2 Golf ball containing graphite nanosheets in a polymeric network ACUSHNET COMPANY 2004-10-12 US claimed
US-20040166962-A1 Golf ball containing graphite nanosheets in a polymeric network ACUSHNET COMPANY 2004-08-26 US claimed
US-6685580-B2 Three-layer cover for a golf ball including a thin dense layer ACUSHNET COMPANY 2004-02-03 US claimed
US-20030224877-A1 Golf ball containing graphite nanosheets in a polymeric network JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-12-04 US claimed
US-20020151382-A1 Three-layer cover for a golf ball including a thin dense layer JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2002-10-17 US claimed
US-20020151381-A1 Three-layer-cover golf ball ACUSHNET COMPANY 2002-10-17 US claimed
US-20180311534-A1 GOLF BALLS HAVING MULTI-LAYERED FOAM CORES WITH STRUCTURAL INSERTS ACUSHNET COMPANY (US) 2018-11-01 US disclosed
US-10010764-B2 Golf balls having multi-layered foam cores with structural inserts ACUSHNET COMPANY (US) 2018-07-03 US disclosed
US-20180133558-A1 THREE-LAYER-CORE GOLF BALL HAVING HIGHLY-NEUTRALIZED POLYMER OUTER CORE LAYER ACUSHNET COMPANY (US) 2018-05-17 US disclosed
US-20180133559-A1 THREE-LAYER-CORE GOLF BALL HAVING HIGHLY-NEUTRALIZED POLYMER OUTER CORE LAYER ACUSHNET COMPANY (US) 2018-05-17 US disclosed
US-20170209746-A1 THREE-LAYER-CORE GOLF BALL HAVING HIGHLY-NEUTRALIZED POLYMER OUTER CORE LAYER ACUSHNET COMPANY (US) 2017-07-27 US disclosed
US-9616296-B2 Three-layer-core golf ball having highly-neutralized polymer outer core layer ACUSHNET COMPANY (US) 2017-04-11 US disclosed
US-20030092509-A1 Golf ball covers comprising modulus adjusting fillers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-05-15 US disclosed
US-20030083153-A1 Golf ball having a non-uniform thickness layer JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-05-01 US disclosed
US-20030022731-A1 Golf ball with high coefficient of restitution JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-01-30 US disclosed
US-20020198064-A1 Golf ball having a high moment of inertia and low driver spin rate ACUSHNET COMPANY 2002-12-26 US disclosed
US-20020169037-A1 Golf ball having a high moment of inertia and low driver spin rate JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2002-11-14 US disclosed
US-20020151382-A1 Three-layer cover for a golf ball including a thin dense layer JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2002-10-17 US disclosed
US-20020151381-A1 Three-layer-cover golf ball ACUSHNET COMPANY 2002-10-17 US disclosed