Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.73 |
| ▸ | MEN1 | O00255 | 8/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.73 |
| ▸ | HTT | P42858 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | RAB9A | P51151 | 4/20 | 0.73 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | MITF | O75030 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | NPY1R | P25929 | 1/20 | 0.69 |
| ▸ | NPY2R | P49146 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | MMP14 | P50281 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812204 | 1.00 | MAPT (0.73) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL20523744 | 0.79 | RAPGEF3 (0.79) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL15047067 | 0.79 | MAPT (0.54) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL30611545 | 0.77 | RAPGEF3 (0.79) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL29198747 | 0.77 | RAPGEF3 (0.79) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL11205901 | 0.74 | KMT2A (0.74) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL11205903 | 0.74 | KMT2A (0.74) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL14613033 | 0.73 | MAPT (0.60) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL20523731 | 0.72 | RAPGEF3 (0.75) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL20523734 | 0.72 | RAPGEF3 (0.75) | MAPTMEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0881878-A4 | ARYLHYDRAZONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | ANADYS PHARMACEUTICALS INC (US) | 2004-08-04 | — | — | EP | disclosed |
| EP-0881878-A1 | ARYLHYDRAZONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Scriptgen Pharmaceuticals Inc. (US) | 1998-12-09 | — | — | EP | disclosed |
| US-5760063-A | ANTIBIOTICS | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1998-06-02 | — | — | US | disclosed |
| WO-1997009878-A1 | ARYLHYDRAZONE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1997-03-20 | — | — | WO | disclosed |