Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 13/20 | 0.65 |
| ▸ | HTR1B | P28222 | 8/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.65 |
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812201 | 0.94 | SLC6A4 (0.58) | HTR1DHTR1BSLC6A4DRD2ADRA1D | |
| SCHEMBL6808681 | 0.90 | SLC6A4 (0.54) | HTR1DHTR1BSLC6A4DRD2ADRA1D | |
| SCHEMBL6811244 | 0.88 | SLC6A4 (0.52) | HTR1DHTR1BSLC6A4DRD2ADRA1D | |
| SCHEMBL6811492 | 0.86 | HTR1D (0.64) | HTR1DHTR1BSLC6A4DRD2ADRA1D | |
| SCHEMBL6811694 | 0.82 | HTR1D (0.67) | HTR1DHTR1BSLC6A4DRD2ADRA1D | |
| SCHEMBL6808322 | 0.82 | HTR1D (0.76) | HTR1DHTR1BSLC6A4DRD2ADRA1D | |
| SCHEMBL6811135 | 0.79 | HTR1D (1.00) | HTR1DHTR1BSLC6A4DRD2ADRA1D | |
| SCHEMBL6811345 | 0.79 | HTR1D (1.00) | HTR1DHTR1BSLC6A4DRD2ADRA1D | |
| SCHEMBL6812206 | 0.77 | DRD2 (0.52) | HTR1DHTR1BSLC6A4DRD2ADRA1D | |
| SCHEMBL8319340 | 0.76 | SLC6A4 (0.60) | HTR1DHTR1BSLC6A4DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | CYP2D6, LPXN, CYP1B1 | HTR1D 124/4885HTR1B 373/4885SLC6A4 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.