Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | SHBG | P04278 | 1/20 | 0.69 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | GABRP | O00591 | 2/20 | 0.61 |
| ▸ | GABRD | O14764 | 2/20 | 0.61 |
| ▸ | G6PD | P11413 | 2/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.61 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376650 | 1.00 | LMNA (0.69) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL19750469 | 1.00 | LMNA (0.69) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6812901 | 1.00 | LMNA (0.69) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL25854513 | 1.00 | LMNA (0.69) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6816494 | 1.00 | LMNA (0.69) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL8499073 | 1.00 | LMNA (0.69) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL15426615 | 1.00 | LMNA (0.69) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL15959419 | 0.86 | LMNA (0.52) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL15837753 | 0.86 | LMNA (0.52) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL15959577 | 0.86 | LMNA (0.52) | LMNAGPBAR1CYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9851309-B2 | Ultra-high-sensitive assay of protein and nucleic acid and kit, and novel enzyme substrate | Watabe, Satoshi (JP) | 2017-12-26 | — | — | US | claimed |
| US-11221299-B2 | Ultra-high-sensitive assay of protein and nucleic acid and kit, and novel enzyme substrate | Watabe, Satoshi (JP) | 2022-01-11 | — | — | US | disclosed |
| EP-3296405-B1 | METHOD AND KIT FOR SUPER-HIGH-SENSITIVITY MEASUREMENT OF PROTEIN AND NUCLEIC ACID, AND NOVEL ENZYME SUBSTRATE | ITO ETSURO (JP) | 2019-10-09 | — | — | EP | disclosed |
| US-20180106727-A1 | ULTRA-HIGH-SENSITIVE ASSAY OF PROTEIN AND NUCLEIC ACID AND KIT, AND NOVEL ENZYME SUBSTRATE | BIOPHENOMA INC. (JP) | 2018-04-19 | — | — | US | disclosed |
| EP-3296405-A1 | METHOD AND KIT FOR SUPER-HIGH-SENSITIVITY MEASUREMENT OF PROTEIN AND NUCLEIC ACID, AND NOVEL ENZYME SUBSTRATE | Ito, Etsuro (JP) | 2018-03-21 | — | — | EP | disclosed |
| US-9851309-B2 | Ultra-high-sensitive assay of protein and nucleic acid and kit, and novel enzyme substrate | Watabe, Satoshi (JP) | 2017-12-26 | — | — | US | disclosed |
| EP-2987866-B1 | METHOD AND KIT FOR SUPER-HIGH-SENSITIVITY MEASUREMENT OF PROTEIN AND NUCLEIC ACID, AND NOVEL ENZYME SUBSTRATE | ITO ETSURO (JP) | 2017-12-06 | — | — | EP | disclosed |
| EP-2695948-B1 | Method and kit for super-high-sensitivity measurement of protein and nucleic acid, and novel enzyme substrate | ITO ETSURO (JP) | 2016-12-28 | — | — | EP | disclosed |
| EP-2987866-A2 | METHOD AND KIT FOR SUPER-HIGH-SENSITIVITY MEASUREMENT OF PROTEIN AND NUCLEIC ACID, AND NOVEL ENZYME SUBSTRATE | Ito, Etsuro (JP) | 2016-02-24 | — | — | EP | disclosed |
| EP-2695948-A1 | METHOD AND KIT FOR SUPER-HIGH-SENSITIVITY MEASUREMENT OF PROTEIN AND NUCLEIC ACID, AND NOVEL ENZYME SUBSTRATE | Ito, Etsuro (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-20140017675-A1 | ULTRA-HIGH-SENSITIVE ASSAY OF PROTEIN AND NUCLEIC ACID AND KIT, AND NOVEL ENZYME SUBSTRATE | Nakaishi, Kazunari (JP) | 2014-01-16 | — | — | US | disclosed |
| WO-2012128338-A1 | METHOD AND KIT FOR SUPER-HIGH-SENSITIVITY MEASUREMENT OF PROTEIN AND NUCLEIC ACID, AND NOVEL ENZYME SUBSTRATE | ITO ETSURO (JP) | 2012-09-27 | — | — | WO | disclosed |
| EP-0837874-B1 | NEUROACTIVE STEROIDS OF THE ANDROSTANE AND PREGNANE SERIES | EURO CELTIQUE SA (LU) | 2004-12-15 | — | — | EP | disclosed |
| US-6780853-B1 | FOR MODULATING BRAIN EXCITABILITY | EURO-CELTIQUE S.A. (LU) | 2004-08-24 | — | — | US | disclosed |
| EP-1288220-A2 | Neuroactive 3.alpha.-hydroxy-steroids of the androstane and pregnane series | Purdue Pharma Ltd. (US) | 2003-03-05 | — | — | EP | disclosed |
| US-5925630-A | MODULATION OF BRAIN EXCITABILITY TO RELIEVE STRESS, ANXIETY, INSOMNIA AND MOOD DISORDERS | COCENSYS, INC. (US) | 1999-07-20 | — | — | US | disclosed |
| EP-0837874-A2 | NEUROACTIVE STEROIDS OF THE ANDROSTANE AND PREGNANE SERIES | Cocensys, Inc. (US) | 1998-04-29 | — | — | EP | disclosed |
| WO-1998005337-A1 | USE OF GABA AND NMDA RECEPTOR LIGANDS FOR THE TREATMENT OF MIGRAINE HEADACHE | COCENSYS, INC. (US) | 1998-02-12 | — | — | WO | disclosed |
| WO-1996040043-A2 | NEUROACTIVE STEROIDS OF THE ANDROSTANE AND PREGNANE SERIES | COCENSYS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| US-4297350-A | ORAL ANTIFERTILITY AGENTS; REVERSIBLE | THE UPJOHN COMPANY (US) | 1981-10-27 | — | — | US | disclosed |