Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA3 | P07451 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | CA5A | P35218 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.64 |
| ▸ | MMP8 | P22894 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814514 | 1.00 | CA12 (0.64) | CA12CA1CA2CA3CA4 | |
| SCHEMBL993570 | 1.00 | CA12 (0.64) | CA12CA1CA2CA3CA4 | |
| SCHEMBL24347010 | 0.97 | MMP8 (0.63) | CA12CA1CA2CA3CA4 | |
| SCHEMBL25214759 | 0.88 | MMP8 (0.63) | CA12CA1CA2CA3CA4 | |
| SCHEMBL25214750 | 0.88 | MMP8 (0.63) | CA12CA1CA2CA3CA4 | |
| SCHEMBL25240460 | 0.88 | MMP8 (0.63) | CA12CA1CA2CA3CA4 | |
| SCHEMBL12436634 | 0.87 | MMP8 (0.59) | CA12CA1CA2CA3CA4 | |
| SCHEMBL24345983 | 0.85 | MMP8 (0.54) | CA12CA1CA2CA3CA4 | |
| SCHEMBL8545637 | 0.85 | CA12 (0.66) | CA12CA1CA2CA3CA4 | |
| SCHEMBL24347008 | 0.84 | MMP8 (0.63) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38551-E1 | ADMINISTERING N-BENZYL-2- ACETAMIDO PROPIONAMIDE DERIVATIVES IN THE R CONFIGURATION, SUCH AS LACOSAMIDE | RESEARCH CORPORATION TECHNOLOGIES, INC. | 2004-07-06 | — | — | US | disclosed |
| EP-1038522-B1 | Anticonvulsant enantiomeric amino acid derivatives | RES CORP TECHNOLOGIES INC (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-0400440-B1 | Amino acid derivative anticonvulsant | RES CORP TECHNOLOGIES INC (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-0888289-B1 | ANTICONVULSANT ENANTIOMERIC AMINO ACID DERIVATIVES | RES CORP TECHNOLOGIES INC (US) | 2001-06-13 | — | — | EP | disclosed |
| EP-1038522-A2 | Anticonvulsant enantiomeric amino acid derivatives | Research Corporation Technologies, Inc (US) | 2000-09-27 | — | — | EP | disclosed |
| EP-0888289-A1 | ANTICONVULSANT ENANTIOMERIC AMINO ACID DERIVATIVES | Research Corporation Technologies, Inc (US) | 1999-01-07 | — | — | EP | disclosed |
| US-5773475-A | DIPEPTIDES FOR CENTRAL NERVOUS SYSTEM DISORDERS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1997033861-A1 | ANTICONVULSANT ENANTIOMERIC AMINO ACID DERIVATIVES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-09-18 | — | — | WO | disclosed |
| US-5654301-A | Lacosamide FDA Orange book listed patent | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5378729-A | Diamide derivatives | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |
| WO-1992021648-A1 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-10 | — | — | WO | disclosed |
| WO-1990015069-A2 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-13 | — | — | WO | disclosed |
| EP-0400440-A1 | Amino acid derivative anticonvulsant | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |