Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29205569 | 0.81 | KCNN4 (0.34) | KCNN4ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL2244902 | 0.79 | KCNN4 (0.33) | KCNN4ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL29205572 | 0.77 | KCNN4 (0.38) | KCNN4ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL6813337 | 0.77 | KCNN4 (0.34) | KCNN4ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL10322356 | 0.72 | ESR1 (0.32) | KCNN4ESR1ESR2CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL6817559 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL6809272 | 0.72 | — | — | |
| SCHEMBL827345 | 0.70 | ESR1 (0.56) | KCNN4ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL29205541 | 0.67 | MEN1 (0.32) | KCNN4 | |
| Hydrochloric Acid SCHEMBL2357987 | 0.67 | KCNN4 (0.30) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919574-B1 | Polymerization catalyst, process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared | UBE INDUSTRIES (JP) | 2004-02-11 | — | — | EP | disclosed |
| US-6300450-B1 | Conjugated diene compound polymerization catalyst process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared | UBE INDUSTRIES, LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0919574-A1 | Polymerization catalyst, process for the preparation of conjugated diene polymer in the presence thereof and polybutadiene thus prepared | Ube Industries, Ltd. (JP) | 1999-06-02 | — | — | EP | disclosed |