Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.69 |
| ▸ | POLA1 | P09884 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814213 | 0.89 | KCNH2 (0.67) | KCNH2POLA1MEN1KMT2AF2 | |
| SCHEMBL6288520 | 0.84 | KCNH2 (0.68) | KCNH2POLA1MEN1KMT2AF2 | |
| SCHEMBL6789243 | 0.84 | POLA1 (0.69) | KCNH2POLA1MEN1KMT2AF2 | |
| SCHEMBL6698737 | 0.84 | POLA1 (0.69) | KCNH2POLA1MEN1KMT2AF2 | |
| SCHEMBL6840599 | 0.84 | KCNH2 (0.68) | KCNH2POLA1MEN1KMT2AF2 | |
| SCHEMBL30372497 | 0.83 | MEN1 (0.73) | KCNH2POLA1MEN1KMT2AF2 | |
| SCHEMBL6699690 | 0.83 | MEN1 (0.73) | KCNH2POLA1MEN1KMT2AF2 | |
| SCHEMBL6281183 | 0.83 | KCNH2 (0.71) | KCNH2POLA1MEN1KMT2AF2 | |
| SCHEMBL6694529 | 0.83 | KCNH2 (0.66) | KCNH2POLA1MEN1KMT2AF2 | |
| SCHEMBL6283191 | 0.83 | KCNH2 (0.66) | KCNH2POLA1MEN1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140851-B1 | 4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | UPJOHN CO (US) | 2004-09-01 | — | — | EP | claimed |