Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.75 |
| ▸ | RXRB | P28702 | 2/20 | 0.75 |
| ▸ | F9 | P00740 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758879 | 0.86 | RXRA (1.00) | RXRARXRBBCL2MRGPRX4KMT2A | |
| SCHEMBL18314425 | 0.86 | RXRA (1.00) | RXRARXRBBCL2MRGPRX4KMT2A | |
| SCHEMBL6816376 | 0.85 | KMT2A (0.63) | RXRARXRBMAPTHPGDKDM4E | |
| SCHEMBL3495434 | 0.81 | PLA2G4B (0.68) | MAPTHPGDKDM4EALDH1A1TP53 | |
| SCHEMBL9863137 | 0.81 | PPARA (0.67) | F9F10MAPTHPGDKDM4E | |
| SCHEMBL6569708 | 0.81 | RXRA (0.78) | RXRARXRBBCL2TP53MRGPRX4 | |
| SCHEMBL7028743 | 0.80 | PPARA (0.60) | RXRARXRBF9F10MAPT | |
| SCHEMBL16180353 | 0.80 | F9 (0.54) | RXRARXRBF9F10MAPT | |
| SCHEMBL12297772 | 0.80 | RXRA (0.53) | RXRARXRBF9F10MAPT | |
| SCHEMBL5386249 | 0.80 | MAPT (0.74) | MAPTHPGDKDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011427-A2 | SUBSTITUTED BENZANILIDES AS MODULATORS OF THE CCR5 RECEPTOR | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |