SCHEMBL6814009

SCHEMBL6814009

Cc1c(=O)c(Cc2ccc(C(=O)O)cc2)cn2nc(C#Cc3ccccc3)oc12.Cc1c(=O)c(Cc2ccc(F)c(F)c2)cn2nc(C#Cc3ccccc3)sc12

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.32
P2RY14 Q15391 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6478515 0.86 GRM4 (0.33) P2RY14
SCHEMBL6476082 0.85 TSHR (0.37)
SCHEMBL6814016 0.81
SCHEMBL6485426 0.73 P2RY14 (0.36) P2RY14
SCHEMBL6818812 0.72 CHRM4 (0.37) PTGER4
SCHEMBL6477648 0.70 POLB (0.42) PTGER4
SCHEMBL6477100 0.70 CHRM4 (0.43) PTGER4
SCHEMBL6489375 0.69 GRM4 (0.33)
SCHEMBL6488680 0.69 TSHR (0.38)
SCHEMBL6484250 0.69 FFAR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004014908-A1 HETEROBICYLCIC METALLOPROTEINASE INHIBITORS WARNER-LAMBERT COMPANY LLC (US) 2004-02-19 WO disclosed