Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821776 | 0.83 | NPC1 (0.51) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL6833933 | 0.81 | NPC1 (0.54) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL6818899 | 0.76 | KMT2A (0.57) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL6813729 | 0.75 | TDP1 (0.55) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL6833885 | 0.73 | TDP1 (0.49) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL6818261 | 0.73 | THRB (0.56) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL6830647 | 0.73 | KMT2A (0.49) | NPC1KMT2ARAB9AMEN1NPSR1 | |
| SCHEMBL6833848 | 0.71 | KMT2A (0.56) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL6818791 | 0.71 | HSD17B10 (0.48) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL6834026 | 0.71 | KMT2A (0.46) | NPC1KMT2ARAB9AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |