Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814518 | 1.00 | PLG (0.44) | PLGPLATLMNANCF1 | |
| SCHEMBL402037 | 0.86 | — | — | |
| SCHEMBL1703765 | 0.76 | PLG (0.55) | PLGPLATLMNANCF1 | |
| SCHEMBL6802 | 0.76 | — | — | |
| SCHEMBL432248 | 0.76 | PLG (0.55) | PLGPLATLMNANCF1 | |
| SCHEMBL48375 | 0.76 | PLG (0.55) | PLGPLATLMNANCF1 | |
| SCHEMBL235988 | 0.75 | — | — | |
| SCHEMBL6018785 | 0.75 | — | — | |
| SCHEMBL8792393 | 0.74 | ALDH1A1 (0.32) | LMNA | |
| SCHEMBL927909 | 0.74 | ESR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1079860-B1 | NICOTINE IMMUNOGEN | INDEPENDENT PHARMACEUTICA AB (SE) | 2004-10-27 | — | — | EP | disclosed |
| US-6656469-B1 | Treatment of nicotine dependence from tobacco products | INDEPENDENT PHARMACEUTICA AB (SE) | 2003-12-02 | — | — | US | disclosed |