SCHEMBL68152

SCHEMBL68152

COC(=O)C(Br)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.64
CES2 O00748 2/20 0.59
CES1 P23141 2/20 0.59
MEN1 O00255 2/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
TSHR P16473 2/20 0.44
SLC6A3 Q01959 4/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
DHFR P00374 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL318731 1.00 KMT2A (0.64) KMT2ACES2CES1MEN1PTGS1
SCHEMBL319987 1.00 KMT2A (0.64) KMT2ACES2CES1MEN1PTGS1
SCHEMBL1428029 0.89 KMT2A (0.52) KMT2ACES2CES1PTGS2ALDH1A1
SCHEMBL1565875 0.86 MAPK1 (0.51) KMT2ACES2CES1PTGS1ALDH1A1
SCHEMBL13522785 0.84 KMT2A (0.51) KMT2ACES2CES1MEN1PTGS1
SCHEMBL9000507 0.82 PTGS1 (0.59) KMT2AMEN1PTGS1PTGS2
SCHEMBL8881032 0.82 ESR1 (0.54) KMT2APTGS1ALDH1A1LMNASLC6A3
SCHEMBL4776154 0.82 L3MBTL1 (0.45) KMT2AALDH1A1LMNA
SCHEMBL1564938 0.82 CYP1A2 (0.50) KMT2AMEN1ALDH1A1LMNA
SCHEMBL4013605 0.82 L3MBTL1 (0.46) KMT2AMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 907 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954994-A Method for free radical polymerization based on macro-micro reactor 南京工业大学 2025-05-09 CN claimed
CN-118459631-A Photo-thermal double-switch controllable free radical polymerization method based on quaternary ammonium salt in-situ initiation 苏州大学 2024-08-09 CN claimed
CN-116003682-B Acrylonitrile copolymer and preparation method and application thereof 山西钢科碳材料有限公司 2024-03-01 CN claimed
CN-116003682-A Acrylonitrile copolymer and preparation method and application thereof 山西钢科碳材料有限公司 2023-04-25 CN claimed
CN-115286583-A Diphenylaminopyrimidine-containing compound, preparation and application thereof as HDACs enzyme inhibitor 山东大学 2022-11-04 CN claimed
CN-113061205-B Controllable free radical polymerization method based on C-N bond breakage 苏州大学 2022-03-11 CN claimed
CN-113061205-A Controllable free radical polymerization method based on C-N bond breakage 苏州大学 2021-07-02 CN claimed
US-20190106590-A1 COATING COMPOSITION CONTAINING A SORBIC ACID ESTER AND A PHOTOCATALYST DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-11 US claimed
EP-3440141-A1 COATING COMPOSITION CONTAINING SORBIC ACID ESTER AND PHOTOCATALYST Dow Global Technologies, LLC (US) 2019-02-13 EP claimed
WO-2017173646-A1 COATING COMPOSITION CONTAINING SORBIC ACID ESTER AND PHOTOCATALYST DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-12 WO claimed
WO-2003011917-A1 METHOD OF CURING ELASTOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-02-13 WO claimed
US-12622909-B2 Allosteric EGFR inhibitors and methods of use thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2026-05-12 US disclosed
EP-4159727-B1 INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN MORPHIC THERAPEUTIC INC (US) 2026-04-08 EP disclosed
EP-3773573-B1 ANTAGONISTS OF HUMAN INTEGRIN (ALPHA4)(BETA7) MORPHIC THERAPEUTIC INC (US) 2026-03-18 EP disclosed
EP-4121421-B1 BIARYL DERIVATIVES AS YAP/TAZ-TEAD PROTEIN-PROTEIN INTERACTION INHIBITORS NOVARTIS AG (CH) 2026-03-11 EP disclosed
US-4206120-A Oxaazabicycloheptane antibiotics BEECHAM GROUP LIMITED (GB) 1980-06-03 US disclosed
EP-0010398-A1 Isatin derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-04-30 EP disclosed
US-4166863-A ACTIVE AGAINST HEMOPHILUS AND NEISSERIA BEECHAM GROUP LIMITED (GB) 1979-09-04 US disclosed
US-4102901-A MONIC ACID ESTERS BEECHAM GROUP LIMITED (GB) 1978-07-25 US disclosed
US-4046759-A INTERMEDIATES FOR CEPHALOSPORINS ISHIMARU TOSHIYASU 1977-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622909-B2 Allosteric EGFR inhibitors and methods of use thereof EGFR, ERBB3, ERBB2 KMT2A 2644/4885CES2 2480/4885CES1 1942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.