SCHEMBL681523

SCHEMBL681523

CCCCNC(=S)Nc1c(C(C)C)cc(Oc2ccccc2)cc1C(C)C

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.64
HTT P42858 7/20 0.64
ALDH1A1 P00352 6/20 0.64
GAA P10253 5/20 0.64
KMT2A Q03164 4/20 0.64
NPSR1 Q6W5P4 2/20 0.64
ALOX12 P18054 6/20 0.53
LMNA P02545 7/20 0.49
HPGD P15428 3/20 0.49
SMN1; SMN2 Q16637 4/20 0.48
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
SOAT1 P35610 1/20 0.41
ALPL P05186 2/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27926 0.78 ALDH1A1 (0.47) MAPTHTTALDH1A1GAAKMT2A
SCHEMBL8408960 0.78 ALDH1A1 (0.47) MAPTHTTALDH1A1GAAKMT2A
SCHEMBL28827410 0.77 ALDH1A1 (0.48) MAPTHTTALDH1A1GAAKMT2A
SCHEMBL9780906 0.77 ALDH1A1 (0.48) MAPTHTTALDH1A1KMT2AALOX12
Water SCHEMBL2581834 0.77 ALDH1A1 (0.46) MAPTHTTALDH1A1GAAKMT2A
SCHEMBL9800926 0.76 SOAT1 (0.66) SOAT1
Thiourea SCHEMBL18454051 0.75 ALDH1A1 (0.44) MAPTHTTALDH1A1GAAKMT2A
Pyrrole SCHEMBL28190457 0.74 ALDH1A1 (0.41) MAPTHTTALDH1A1GAAKMT2A
SCHEMBL15693408 0.74 ALDH1A1 (0.46) MAPTHTTALDH1A1GAAKMT2A
SCHEMBL28047919 0.74 ALDH1A1 (0.46) MAPTHTTALDH1A1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100447131-C Method for preparing 1-tert butyl-3-(2,6-diisopropyl-4-phenyl cxypheny) thiourea SHENYANG INST OF CHEMISTRY (CN) 2008-12-31 CN claimed
CN-1911911-A Method for preparing 1-tert butyl-3-(2,6-diisopropyl-4-phenyl cxypheny) thiourea SHENYANG INST OF CHEMISTRY (CN) 2007-02-14 CN claimed
JP-4295405-A None JP disclosed
WO-2026087364-A1 INSECTICIDE COMPOSITION FOR CROPS WITH REDUCED PHYTOTOXICITY SYNGENTA CROP PROTECTION AG (CH) 2026-04-30 WO disclosed
CN-116210712-B Insecticidal composition containing diafenthiuron and application thereof 青岛凯源祥化工有限公司 2024-06-14 CN disclosed
CN-116210712-A Insecticidal composition containing diafenthiuron and application thereof 青岛凯源祥化工有限公司 2023-06-06 CN disclosed
CN-105794810-B A kind of Pesticidal combination and its method for controlling agricultural pests 江苏龙灯化学有限公司 2019-01-29 CN disclosed
CN-103814930-B A kind of Pesticidal combination and its application containing thiacloprid and diafenthiuron 浙江威尔达化工有限公司 2018-08-31 CN disclosed
CN-104082336-B Efficient Compositional acaricide RESEARCH INSTITUTE OF SILKWORMS, MULBERRIES AND BEES, YUNNAN ACADEMY OF AGRICULTURAL SCIENCES (CN) 2017-01-04 CN disclosed
CN-105794810-A Insecticidal composition and agricultural insect control method 江苏龙灯化学有限公司 2016-07-27 CN disclosed
CN-103651537-B The ultra low volume liquids of fluorine silicon chrysanthemum ester and insect growth regulator, IGR insecticides 广西田园生化股份有限公司 2016-06-29 CN disclosed
EP-1982594-A1 Active agent combinations with insecticidal and acaricidal properties Bayer CropScience AG (DE) 2008-10-22 EP disclosed
CN-100417324-C Compsn. of agricultural pesticide and preparation method UNIV BEIJING CHEMICAL (CN) 2008-09-10 CN disclosed
CN-101213970-A Pesticide composition containing thiodicarb effective component and application thereof SHAOWU ZHANG (CN) 2008-07-09 CN disclosed
CN-101194622-A Effervescence tablet containing emamectin benzoate-chlorfenapyr active ingredient, its preparation method and application SHAOWU ZHANG (CN) 2008-06-11 CN disclosed
US-20080027114-A1 Active Agent Combinations with Insecticidal and Acaricidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2008-01-31 US disclosed
WO-2008006513-A1 ACTIVE INGREDIENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER CROPSCIENCE AG (DE) 2008-01-17 WO disclosed
CN-1911911-A Method for preparing 1-tert butyl-3-(2,6-diisopropyl-4-phenyl cxypheny) thiourea SHENYANG INST OF CHEMISTRY (CN) 2007-02-14 CN disclosed
CN-1695446-A Compsn. of agricultural pesticide and preparation method UNIV BEIJING CHEMICAL (CN) 2005-11-16 CN disclosed
JP-H04295405-A ACARICIDAL COMPOSITION CIBA GEIGY AG 1992-10-20 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027114-A1 Active Agent Combinations with Insecticidal and Acaricidal Properties AADAC, ACAA2, AAAS MAPT 4229/4885HTT 2916/4885ALDH1A1 1621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.