Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811101 | 0.92 | MAPT (0.56) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL7979004 | 0.88 | MAPT (0.71) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL6815562 | 0.84 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL6814745 | 0.83 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL6815350 | 0.83 | MAPT (0.64) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL6811902 | 0.82 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL6819388 | 0.82 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL6814080 | 0.82 | MAPT (0.63) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL6815615 | 0.81 | ALDH1A1 (0.81) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7745937 | 0.80 | MAPT (0.61) | MAPTALDH1A1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137645-B1 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | WYETH CORP (US) | 2004-05-26 | — | — | EP | disclosed |
| US-6555561-B2 | N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus | WYETH | 2003-04-29 | — | — | US | disclosed |
| US-6262090-B1 | Aminopyridine-containing thiourea inhibitors of herpes viruses | AMERICAN HOME PRODUCTS CORPORATION | 2001-07-17 | — | — | US | disclosed |
| US-6201013-B1 | INOSINE MONOPHOSPHATE DEHYDROGENASE (IMPDH) INHIBITOR; SIDE EFFECT REDUCTION, NON-DRUG RESISTANT | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-13 | — | — | US | disclosed |