SCHEMBL68156

SCHEMBL68156

NC(=O)CCC(=O)NBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethyl Sulfoxide SCHEMBL25289758 0.87
SCHEMBL10568267 0.86 HDAC3 (0.42)
SCHEMBL16401947 0.85 NFKB1 (0.41)
Succinamide SCHEMBL36057 0.74
SCHEMBL131291 0.74
SCHEMBL137189 0.74
SCHEMBL14967033 0.74
SCHEMBL20243513 0.72
SCHEMBL9260965 0.72 PHF8 (0.55)
SCHEMBL4384899 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3888 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492220-B2 Method for the preparation of oligonucleotides THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2025-12-09 US claimed
WO-2025074394-A1 A PROCESS FOR THE PREPARATION OF BELZUTIFAN AND ITS NOVEL INTERMEDIATES THEREOF NATCO PHARMA LIMITED (IN) 2025-04-10 WO claimed
EP-3676260-B1 THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF FOR THE TREATMENT OF AUTOIMMUNE DISORDERS AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2024-10-30 EP claimed
WO-2024150245-A1 PROCESS FOR PREPARATION OF RELUGOLIX INTERMEDIATES AARTI PHARMALABS LIMITED (IN) 2024-07-18 WO claimed
WO-2024142096-A1 PROCESS FOR PREPARATION OF NIRAPARIB TOSYLATE AND ITS INTERMEDIATES DR. REDDY’S LABORATORIES LIMITED (IN) 2024-07-04 WO claimed
US-11912654-B2 Process for stereospecific synthesis of vitamin K2 and its novel intermediates SYNERGIA LIFE SCIENCES PVT. LTD. (IN) 2024-02-27 US claimed
CN-111295371-B Improved method for preparing trifloxystrobin 海蔻有限公司 2023-11-21 CN claimed
CN-116744933-A Methods for preparing bisheteroaryl compounds and crystalline forms thereof 基因泰克公司 2023-09-12 CN claimed
US-11739082-B2 Thiophene compounds, process for synthesis and use thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2023-08-29 US claimed
EP-4222154-A1 PROCESS FOR THE PREPARATION OF BIHETEROARYL COMPOUNDS AND CRYSTAL FORMS THEREOF GENENTECH, INC. (US) 2023-08-09 EP claimed
EP-1162962-A1 ALKYNYL ARYL SULFONES LONZA INC. (US) 2001-12-19 EP claimed
EP-1118616-A1 Process for the production of 5'-nor-anhydrovinblastine ditartrate from plants of genus catharanthus Eriochem, S.A. (AR) 2001-07-25 EP claimed
US-6232503-B1 MICROBIOCIDES LONZA INC. 2001-05-15 US claimed
WO-2000056305-A1 ALKYNYL ARYL SULFONES LONZA INC. (US) 2000-09-28 WO claimed
US-6114541-A Method for the preparation of α-Bromo-Lactam derivatives HOFFMANN-LA ROCHE INC. (US) 2000-09-05 US claimed
US-5646300-A NEUROPROTECTIVE AGENTS HOECHST MARION ROUSSEL, INC. (US) 1997-07-08 US claimed
EP-0643709-A1 4-(1-$i(H)-PYRROL-1-YL)IMIDAZOLES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY WARNER-LAMBERT COMPANY (US) 1995-03-22 EP claimed
US-5260449-A Method for preparing 7-oxabicycloheptyl substituted bromooxazole amide prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds E. R. SQUIBB & SONS, INC. (US) 1993-11-09 US claimed
WO-1993000341-A1 4-(1-H-PYRROL-1-YL)IMIDAZOLES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY WARNER-LAMBERT COMPANY (US) 1993-01-07 WO claimed
US-4263443-A HEATING WITH ALCOHOL, RHODIUM OR IRIDIUM HALCON RESEARCH AND DEVELOPMENT CORP. (US) 1981-04-21 US claimed